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The secret life of a cell-cycle gatekeeper of breast cancer

Published: 09/07/2026, 12:00 AM

Cristina Guarducci is in the Translational Research Unit, Department of Oncology, Azienda USL Toscana Centro, Hospital of Prato, 59100 Prato, Italy. Search author on: PubMed Google Scholar Luca Malorni is in the Translational Research Unit, Department of Oncology, Azienda USL Toscana Centro, Hospital of Prato, 59100 Prato, Italy. Search author on: PubMed Google Scholar A fuller picture of the actions of proteins that regulate cell division could help researchers to develop treatments for certain tumour types. Writing in Nature, Watt et al.1 unmask a new role for the tumour-suppressor protein Rb in breast cancer, showing that it can promote gene expression and influence the response of cancer cells to therapy. Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription Prices may be subject to local taxes which are calculated during checkout Osborne, C. K. & Schiff, R. Ann. Rev. Med. 62, 233–247 (2011). Article PubMed Google Scholar